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Minoru Sasano Selected Research

1- (2- (1- adamantyl)ethyl)- 1- pentyl- 3- (3- (4- pyridyl)propyl)urea

2/2010Transient receptor potential vanilloid 1 agonists as candidates for anti-inflammatory and immunomodulatory agents.
1/2010Effects of SA13353, a transient receptor potential vanilloid 1 agonist, on leukocyte infiltration in lipopolysaccharide-induced acute lung injury and ovalbumin-induced allergic airway inflammation.
7/2008SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo.

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Minoru Sasano Research Topics

Disease

5Rheumatoid Arthritis
10/2020 - 07/2008
5Arthritis (Polyarthritis)
01/2019 - 03/2002
2Hyperalgesia
12/2011 - 11/2010
2Inflammation (Inflammations)
02/2010 - 01/2010
1Bone Resorption
01/2019
1B-Cell Lymphoma (Lymphoma, B Cell)
09/2012
1Chronic Pain
12/2011
1Pain (Aches)
12/2011
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
02/2010
1Lung Injury
01/2010
1Encephalomyelitis (Myeloencephalitis)
01/2010
1Acute Lung Injury
01/2010
1Experimental Arthritis
07/2008
1Hypoxia (Hypoxemia)
12/2007
1Sepsis (Septicemia)
03/2002

Drug/Important Bio-Agent (IBA)

4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019 - 03/2002
31- (2- (1- adamantyl)ethyl)- 1- pentyl- 3- (3- (4- pyridyl)propyl)ureaIBA
02/2010 - 07/2008
2Methotrexate (Mexate)FDA LinkGeneric
10/2020 - 09/2012
2bucillamine (SA 96)IBA
09/2012 - 09/2009
23- acetyl- 6- chloro- 2- (2- (3- (N- (2- ethoxyethyl)- N- isopropylamino)propoxy)- 5- methoxyphenyl)benzothiazoline O,O'-diacetyl-L-tartrateIBA
12/2011 - 11/2010
2Morphine (MS Contin)FDA LinkGeneric
12/2011 - 11/2010
2LipopolysaccharidesIBA
02/2010 - 01/2010
1Proteins (Proteins, Gene)FDA Link
01/2019
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2019
1Pharmaceutical PreparationsIBA
01/2019
1Tacrolimus (Prograf)FDA LinkGeneric
01/2019
1Etanercept (Enbrel)FDA Link
01/2019
1Calcineurin InhibitorsIBA
01/2019
1Rheumatoid FactorIBA
09/2012
1Hypnotics and Sedatives (Sedatives)IBA
12/2011
1Analgesics (Analgesic Drugs)IBA
12/2011
1kappa Opioid Receptors (kappa Opioid Receptor)IBA
12/2011
1asimadolineIBA
11/2010
1AntipruriticsIBA
11/2010
1AcidsIBA
11/2010
1Silver NitrateIBA
11/2010
1Substance PIBA
11/2010
1Tramadol (K315)FDA LinkGeneric
11/2010
1(trans)-Isomer 3,4- Dichloro- N- methyl- N- (2- (1- pyrrolidinyl)- cyclohexyl)- benzeneacetamideIBA
11/2010
1CytokinesIBA
02/2010
1Interleukin-4 (Interleukin 4)IBA
01/2010
1OvalbuminIBA
01/2010
1Interleukin-12 Subunit p40IBA
01/2010
1Transcription Factors (Transcription Factor)IBA
12/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2007
1Matrix Metalloproteinases (MMPs)IBA
03/2002
1AntibodiesIBA
03/2002
1ADAM17 ProteinIBA
03/2002
1marimastatIBA
03/2002

Therapy/Procedure

1Ligation
12/2011